Origins and Fates of Cardiovascular Progenitor Cells

I-35: Genetic Aberrations in Early Development:The Origins and The Fates

Genetic aberrations are commonly seen in human preimplantation embryos. Non-disjunction and premature division of a chromosome are common in both meiosis and mitosis divisions. The expected result for meiotic aneuploidies is full aneuploidy in the later stages whereas mosaicism is the most frequent event in the cleavage and blastocyst stages. The main causes for mosaicism are post-zygotic event...

Endothelial Progenitor Cell Dysfunction in Polycystic Ovary Syndrome: Implications for The Genesis of Cardiovascular Diseases

The Impact of High-Intensity Interval Training Versus Moderate-Intensity Continuous Training on Endothelial Progenitor Cells in Overweight Women

Introduction: Obesity is linked to cardiovascular diseases, characterized by endothelial dysfunction, the optimal mode of exercise for controlling obesity of high-intensity interval training or moderate-intensity continuous training has is the however not yet been determined. Materials and Methods: A total of 33 inactive and overweight women, aged 40-50 years with body mass index over 27kg/m2 w...

Effect of 8-week resistance training on HIF-1α gene expression and Endothelial Progenitor Cells recall of blood after one session of resistance activity in elderly men

Abstract Background and Objectives Dysfunction of endothelial cells is associated with the development of atherosclerosis and cardiovascular disease. Adult endothelial progenitor cells are derived from hematopoietic stem cells capable of forming new blood vessels through a process of angiogenesis. This study was to investigate the effect of resistance training on HIF-1α gene expression and rec...

Mesenchymal Stem Cells: Signaling Pathways in Transdifferentiation Into Retinal Progenitor Cells

Several signaling pathways and transcription factors control the cell fate in its in vitro development and differentiation. The orchestrated use of these factors results in cell specification. In coculture methods, many of these factors secrete from host cells but control the process. Today, transcription factors required for retinal progenitor cells are well known, but the generation of these ...